Antisense RNA is an RNA that is composed of only one strand and has a sequence that is complementary to the messenger RNA. The antisense RNA and an mRNA form hybridization and hence the process of translation are blocked and no protein is formed. The naturally occurring antisense RNA exists in both prokaryotes and eukaryotes.
They may be classified into short non-coding RNAs. The short ones are composed of less than 200 nucleotides whereas those who have more than 200 nucleotides are termed as long non-coding RNAs. The primary role of antisense RNA is to control and regulate the expression of genes. They are widely used in the knockdown of genes and have many therapeutic applications too.
Review the concept of an RNA world described in Section 17.
Discuss the advantages and disadvantages of genetic regulation at the different points
Several research studies are under way that involve the use of gene
How does micF antisense RNA affect the translation of ompF mRNA?
