RAG is known as the recombination activating gene and it serves the role of encoding the parts of the protein complexes. These proteins play a significant role in the rearrangement as well as the recombination of those genes that encode the molecules of immunoglobins and T-cell receptors. There are two forms of RAG i.e., RAG1 and RAG2.
During the developmental stages of these genes, their expression in the cell is limited to the lymphocytes. There are several enzymes that are encoded by RAGs and they help in the formation of mature lymphocytes (B-cells and T-cells) which are the essential and critical elements of the adaptive immune system.
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